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Cisplatin induced hyponatremia

WebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude … WebJan 1, 2024 · Univariable analysis revealed a high incidence of hyponatremia in patients receiving cisplatin, three-drug combination regimen, two-drug combination regimen with amrubicin or irinotecan, or high-dose cisplatin (weekly equivalent cisplatin dose ≥20 mg/m2), and in patients with small-cell lung cancer. Conclusion

Neoadjuvant therapy with camrelizumab plus gemcitabine and cisplatin …

WebJul 1, 2008 · Hyponatremia associated with platinum compounds is described more frequently with cisplatin than with carboplatin. 42, 43 The possible underlying pathophysiological mechanisms by which cisplatin induces hyponatremia are SIADH and renal salt wasting. 44 Cisplatin-induced hyponatremia often is combined with … WebCDDP-induced hyponatremia has also occurred in a case of renal salt-wasting syndrome, 4 in patients with nausea/vomiting/anorexia, and when vigorous hydration was … birth certificates online minnesota https://kozayalitim.com

PROFOUND HYPONATREMIA AND DEHYDRATION: A CASE OF CISPLATIN INDUCED …

WebThe possibility of Cisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1mg twice daily, oral salt tablets 1g QID, sodium bicarbonate tablets 650mg TID and normal saline at 150ml/h. ... PROFOUND HYPONATREMIA AND DEHYDRATION: A CASE OF CISPLATIN INDUCED SALT LOSING NEPHROPATHY. … WebJul 22, 2024 · Cisplatin is a potent and valuable chemotherapy agent used to treat a broad spectrum of malignancies. Renal tubular dysfunction and a cumulative impairment in kidney function, as manifested by a decline in the glomerular filtration rate (GFR), can be dose … WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting syndrome … birth certificates online mn

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Category:Cancer therapy-induced hyponatremia: A case …

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Cisplatin induced hyponatremia

Electrolyte disorders with platinum-based chemotherapy …

WebAug 1, 2002 · We report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the … WebDec 21, 2024 · Inamori M, Inohara H, Horii A. Differential diagnosis of hyponatremia induced by cisplatin-con taining chemotherapy: syndrome of inappropriate secretion of an tidiuretic hormone (SIADH) or renal ...

Cisplatin induced hyponatremia

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WebFluid restriction is the hallmark of SIADH treatment, while increased sodium intake remains the hallmark of RSWS treatment. 6 This patient presented with a combination of cisplatin-induced acute kidney injury (AKI) and … WebDec 16, 2024 · Cisplatin induces acute ischemic injury, resulting in decreased renal medullary blood flow ( 24) and renal tubular cell damage ( 25 ). Meanwhile, cisplatin can block calcium ion channels to reduce COX-2 and prostaglandin, cause vasoconstriction, and eventually lead to aggravation of hypoxia ( 26 ).

WebIntroductionLung cancer (LC) is highly prevalent worldwide, with elevated mortality. In this population, taste and smell alterations (TSAs) are frequent but overlooked symptoms. The absence of effective therapeutic strategies and evidence-based WebCisplatin-Induced Acute Kidney Injury and Renal Salt Wasting Syndrome. A treatment strategy that incorporates both water restrictions and sodium supplementation may be appropriate when differentiating between diagnoses of renal salt wasting syndrome and syndrome of inappropriate antidiuretic hormone secretion.

WebMar 1, 2024 · Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude of renal disorders including …

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WebHyponatremia (Surgery-induced Hyponatremia Model) Leukopenia (Cyclophosphamide-induced Leukopenia Model) Hepatic and Biliary Disorders. ... Cisplatin Induced Hearing Loss Model ; Noise Induced Hearing Loss Model; In Vitro Research Model . Cochlea Explant Culture ; Ototoxicity Evaluation. birth certificates online nevadaWebNational Center for Biotechnology Information daniel jung mathe hefteWebThe syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a condition characterized by hypotonic and euvolemic hyponatremia along with urinary hyperosmolarity, resulting from antidiuretic hormone (ADH) release in the absence of adequate stimuli. This term was first used in 1957, when Schwartz et al described … daniel kammer banc of californiaWebWe report a rare case of severe hyponatremia due to cisplatin-induced syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in a 74-year-old male with a … birth certificates online louisianaWebMar 1, 2024 · We report a rare case of cisplatin-induced acute hyponatremia leading to a seizure and coma. A 66-year-old woman with breast cancer received adjuvant … birth certificates online mississippiWebPhysicians may not always give proper attention in time to undesirable drug-induced hyponatremia. Effective clinical management can be handled through awareness of the adverse effect of certain ... Platinum compounds (cisplatin, carboplatin)42-44 Alkylating agents (intravenous cyclophosphamide,45-47 melphalan,48 ifosfamide49) daniel keating university of michiganWebFeb 1, 1995 · Cisplatin, pharmacology and clinical applications Article Feb 2012 S. Ithimakin View Show abstract A Case of Severe Hyponatremia Caused by Renal Salt Wasting Syndrome in Oropharyngeal Cancer... birth certificates online new